Quick Info

Application Deadline: 
October 18, 2024

Fellowship Period:
One (1) year
July 2025 to June 2026

Fellowship Location:
Alnylam Pharmaceuticals, Inc.
675 West Kendall St.
Cambridge, MA 02142

Number of Fellowships Available:
Up to two (2)

Application deadline extended to October 18!

Alnylam Pharmaceuticals has partnered with the Medical Toxicology Foundation on an exciting, unique, one year fellowship in patient safety and risk management!

Fellowship Overview

Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020 and AMVUTTRA ® (vutrisiran) in 2022. Alnylam is advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

Alnylam is proud to have been recognized as one of The Boston Globe’s Top Places to Work nine years in a row (2015-2023). Please visit www.alnylam.com for more information.

Alnylam, based in Cambridge, MA, is offering a one-year paid Global Patient Safety and Risk Management (GPSRM) Physician Fellowship for medical toxicologists including fellows graduating in 2025, recent grads and those who may already be mid-career. This fellowship provides an opportunity for medical toxicologists to gain the skills, knowledge, and experience needed to pursue a career in the competitive biopharmaceutical industry, enabling them to become successful leaders and innovators in various areas of drug development.

The GPSRM team oversees all activities related to the detection, assessment, understanding, and prevention of adverse effects or other medicine-related safety concerns to ensure safe use of medicines and to safeguard health of patients. The fellow can expect to gain a thorough understanding and hands-on experience of pharmacovigilance (PV) activities and actively participate in the development and maintenance of the drug safety profiles for our revolutionary RNAi platform.

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Summary of Key Responsibilities

• Provide scientific and operational assistance to safety product leads to support the ongoing development of Alnylam products
• Participate in collection, interpretation and presentation of safety data in internal forums, including but not limited to Safety Risk Management Team meetings
• Participate in signal detection and management activities under the lead of safety physicians and PV scientists
• Engage in ongoing safety data review, analysis, and reporting of safety data to internal and external stakeholders including HCPs and Regulatory Agencies
• Provide scientific and operational support to planning, management and authoring of safety aggregate reports (PBRERs, DSURs)
• Participate in development and management of Risk Management Plans
• Assist in the process of global literature review

Qualifications

Alnylam prides itself on its entrepreneurial, fast-paced environment where success is rapidly rewarded. There is a strong pipeline, significant resources, and every intention of continuing the phenomenal rate of success and growth. The culture values hard-work, creativity, flexibility, a sense of humor and a hands-on, problem-solving attitude.  

The ideal candidate will have the following mix of personal and professional characteristics:

• Medical Degree (MD) with a completed Residency program.
• Completed Medical Toxicology fellowship.
• Sound clinical acumen and a wide range of therapeutic area knowledge.
• Ability to synthesize and analyze safety data from various sources.  
• Proficiency in problem-solving within a highly complex environment.
• Strong communications skills, both written and spoken, ideally with demonstrable experience in medical / scientific writing.
• Excellent interpersonal and decision-making skills. Strong influencing skills with the ability to quickly earn credibility across other functional areas. 
• Ability to work in a fast-paced environment with rapidly approaching timelines.
• Knowledge of clinical research methodology, clinical epidemiology and biostatistics tools preferred.
• Experience in clinical development is a benefit but not required.

The Role and Liability of the MTF

The Medical Toxicology Foundation has been asked by Alnylam Pharmaceuticals to help with the search for candidates for this position given Alnylam’s desire to recruit medical toxicologists. The MTF assumes no financial or other liability of any kind related to the conducting of the fellowship.  As a condition of accepting the role, the fellow and Alnylam Pharmaceuticals, Inc., indemnify the MTF against any and all liability rising from the conduct of anyone involved with the fellowship. 

A program evaluation will be required from the fellow and the primary Alnylam Pharmaceuticals contact. This evaluation will be developed by the MTF and provided within 15 days of the end of the program.

Contact Information

Any questions regarding this opportunity should be sent by email to Mimi Bajagich at mimi.bajagich@acmt.net.

Alnylam Pharmaceuticals is an EEO employer committed to an exciting, diverse, and enriching work environment.