Impact Story: James Cao, MD

James Cao, MD
2022 Innovative Research, Teaching and Practice Grant 

Grant Project: “Molecularly Designed Polymers for Specific Bupropion Neutralization”
Award Amount: $20,000

About Dr. Cao

Dazhe (James) Cao, M.D., is an Associate Professor and Division Chief of Medical Toxicology in the Department of Emergency Medicine at UT Southwestern Medical Center. Dr. Cao earned his medical degree at Baylor College of Medicine. He completed a residency in emergency medicine at Carolinas Medical Center and received advanced training in medical toxicology through a fellowship at Rocky Mountain Poison & Drug Safety. He is currently the Medical Director of Toxicology for the Parkland Health & Hospital System. Dr. Cao has delivered numerous national and regional invited lectures, contributed to the eleventh edition of the textbook Goldfrank's Toxicologic Emergencies, and published several academic articles.  

Q: In your opinion, how valuable are research opportunities for junior investigators?

A: Research opportunities for junior investigators are extremely valuable. As a fellowship director and division chief of medical toxicology, I focus on the career development of medical toxicology fellows and junior fellows. These opportunities provide crucial experience in grant writing, access to funding for conducting research, and an important addition to their CVs, all of which are essential for their professional growth and future success.

Q: You received a 2022 Innovative Research, Teaching & Practice Grant from the MTF. What updates can you share regarding your project “Molecularly Designed Polymers for Specific Bupropion Neutralization?"

A: We are setting up the animal study that has been approved by the UTSW IACUC. We are ready for the technical portions of the study. We have optimized and synthesized two biopolymers for in vivo testing.

Q: Were there any noteworthy lessons learned that you have since applied to other grant opportunities?

A: Yes, we learned several noteworthy lessons that have since been applied to other grant opportunities. We gained valuable animal study skills, such as intubation, phlebotomy, and oral gavage, and learned how to conduct these studies on campus effectively. Additionally, we discovered the importance of collaborative work with researchers at other institutions, which has enhanced our research capabilities and broadened our network for future projects.